Dialogues in Cardiovascular Medicine
is part of the continuing education programs
of the International Society for Heart Research,
of the European Society of Cardiology,
and of the Italian Society of Cardiology
This is made possible through
an unrestricted educational grant
from Servier
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The last decade has seen the complete sequencing of
the human genome and the development of approaches
to deliver therapeutic genes to the heart. Equally significant
advances have also been made in stem cell
biology... |
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With the advancement of vectors,
delivery methods, and newly identified
molecular targets, preclinical
studies have shown that gene
transfer is effective in improving
left ventricular contractility and
attenuating deleterious left ventricular
remodeling in myocardial
infarction–associated congestive
heart failure (CHF)... |
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Ventricular tachycardia and/or
fibrillation result in 200 000 -
400 000 sudden cardiac deaths
each year in the US alone and atrial
fibrillation currently afflicting
up to 2.3 million Americans each
year... |
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