Dialogues in Cardiovascular Medicine - Vol 7 . No. 2 . 2002






Predictive implications of stress testing. Follow-up of 2700 subjects after maximum treadmill stress testing
M. H. Ellestad, M. K. Wan

Prior to the publication of this paper, controversy had surrounded the usefulness of exercise testing in reliably diagnosing coronary artery disease...



Value of the history and physical in identifying patients at increased risk for coronary events
D. B. Pryor, L. Shaw, C.B. McCants, K. L. Lee, D. B. Mark, F. E. Harrell Jr, L. H. Muhlbaier, R. M. Califf

Much has been written about the predictive value of noninvasive testing in evaluating patients with cardiac symptoms for the likelihood of coronary artery disease (CAD), assessing prognosis, and guiding the need for further investigation...



Survival of medically treated patients in the coronary artery surgery study (CASS) registry
M. B. Mock, I. Ringqvist, L. D. Fisher, K. B. Davis, B. R. Chaitman, N.T. Kouchoukos, G. C. Kaiser, E. Alderman, T. J. Ryan, R. O. Russel Jr, S. Mullin, D. Fray, T. Killip 3rd

Prior to the widespread use of coronary angiography to quantify atherosclerotic burden, studies had reported varying survival rates for patients with coronary artery disease (CAD), ranging from 15% to 75% at 5 years...



Collaborative overview of randomised trials of antiplatelet therapy—I: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients
Antiplatelet Trialists’ Collaboration

As far back as the fifth century BC, Hippocrates made therapeutic use of willow bark to ease aches and reduce fever...



Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

For the best part of the last century, the observation that atherosclerotic plaque contains a lipidrich core has fuelled the belief that the buildup of coronary atherosclerosis is a direct result of high serum cholesterol...



Circadian variation of total ischaemic burden and its alteration with anti-anginal agents
D. Mulcahy, J. Keegan, D. Cunningham, A. Quyyumi, P. Crean, A. Park, C. Wright, K. Fox

How antianginal therapy impacts upon the circadian variation of ischemic episodes in patients with coronary artery disease is illustrated in this important paper...



The pathogenesis of atherosclerosis: a perspective for the 1990s
R. Ross

In this landmark review, the late Russell Ross has not only provided a perspective for the 1990s, but also insight into fundamental shifts in therapeutics extending into the first decade of the millennium...



Analysis of probability as an aid in the clinical diagnosis of coronary-artery disease
G. A. Diamond, J. S. Forrester

Diamond and Forrester provide an interesting insight into the planning of noninvasive tests to diagnose coronary artery disease (CAD)...



Effect of coronary artery bypass graft surgery on survival: overview of 10-year results from randomised trials by the Coronary Artery Bypass Graft Surgery Trialists Collaboration
S. Yusuf, D. Zucker, P. Peduzzi, L. Fisher, T. Takaro, J. W. Kennedy, K. Davis, T. Killip, E. Passamani, R. Norris, et al

This paper complements Bucher’s meta-analysis of percutaneous transluminal coronary angioplasty (PTCA) versus medical therapy...



Percutaneous transluminal coronary angioplasty versus medical treatment for non-acute coronary heart disease: meta-analysis of randomised controlled trials
H. C. Bucher, P. Hengstler, C. Schindler, G. H. Guyatt

The efficacy of percutaneous transluminal coronary angioplasty (PTCA) versus medical therapy in the treatment of stable coronary disease has not been addressed with the same level of interest as the comparison of PTCA with coronary artery bypass surgery (CABG)...






© 2010 LES LABORATOIRES SERVIER, an incorporated company of SERVIER All Rights Reserved - Updates