Sudden death in young athletes
B. J. Maron, W. C. Roberts, H. A. McAllister, D. R. Rosing, S. E. Epstein

Athletes are regarded as the healthiest segment of the population by the medical and lay community and, as a result, the sudden and unexpected death of these individuals, although uncommon, raises profound attention and publicity...

An overview of randomized trials of rehabilitation with exercise after myocardial infarction
G. T. O’Connor, J. E. Buring, S. Yusuf, S. Z. Goldhaber, E. M. Olmstead, R. S. Paffenbarger Jr, C. H. Hennekens

Over one million individuals in the USA suffer myocardial infarction and over 60% survive the initial event...

The athletic heart syndrome
T. P. Huston, J. C. Puffer, W. M. Rodney

Athletic heart syndrome encompasses a constellation of cardiac findings seen in the highly trained athlete...

The incidence of primary cardiac arrest during vigorous exercise
D. S. Siscovick, N. S. Weiss, R. H. Fletcher, T. Lasky

Several epidemiological studies have suggested that regular habitual exercise is associated with decreased cardiovascular morbidity and mortality and a reduction in the risk of sudden cardiac death...

Triggering of acute myocardial infarction by heavy physical exertion. Protection against triggering by regular exertion. Determinants of Myocardial Infarction Onset Study Investigators
M. A. Mittleman, M. Maclure, G. H. Tofler, J. B. Sherwood, R. J. Goldberg, J. E. Muller

The American Heart Association (AHA) recommends increasing physical activity as an important means of reducing the risk of myocardial infarction (MI)...

The upper limit of physiologic cardiac hypertrophy in highly trained elite athletes
A. Pelliccia, B. J. Maron, A. Spataro, M. A. Proschan, P. Spirito

Long-term regular physical training leads to structural adaptations, eg, increased left ventricular (LV) wall thickness, LV end-diastolic cavity diameter, and LV mass, characterizing the “athlete’s heart.”...

Screening for hypertrophic cardiomyopathy in young athletes
D. Corrado, C. Basso, M. Schiavon, G. Thiene

Most sudden deaths (SD) in athletes are due to cardiovascular disease, with nearly half of SDs in young athletes being due to hypertrophic cardiomyopathy (HCM)...

Investigation of the physiological basis for increased exercise threshold for angina pectoris after physical conditioning
D. N. Sim, W. A. Neill

In patients with coronary artery disease, physical conditioning can increase the exercise threshold for angina...

Physical activity and the incidence of coronary heart disease
K. E. Powell, P. D. Thompson, C. J. Caspersen, J. S. Kendrick

Nowadays, the beneficial effects of regular exercise on cardiovascular health are well established, with physicians prescribing regular exercise, as well as statins, aspirin, and angiotensin-converting enzyme (ACE) inhibitors, to individuals deemed to be at risk of coronary heart disease (CHD)...

Exertion and acute coronary artery injury
A. Black, M. M. Black, G. Gensini

Our understanding of the pathogenesis of the acute coronary syndromes has progressed significantly over the last three decades...