Is catheter isolation of the pulmonary veins
a curative procedure for atrial fibrillation? |
Over the last decade, catheter ablation
of atrial fibrillation (AF) has
evolved from an attempt to replicate
the surgical maze procedure to a
more easily achieved goal of pulmonary
vein isolation. Once the
importance of the pulmonary veins
in the initiation of AF episodes was
discovered, catheter ablation approaches
evolved from focal ablation
within the pulmonary veins,
through segmental ostial ablation
(paroxysmal AF), to the current approach
of left atrial extraostial encirclements
of the pulmonary veins
(paroxysmal or persistent AF). This
approach not only isolates the source
of premature beats and triggers of
AF, but is also thought to affect the
substrate of AF maintenance. Current
efforts are directed at the development
of coil- and balloon-based
catheter ablation systems using alternative
energy sources. It is hoped
that these new technologies will
provide an alternative to antiarrhythmic
drug therapy as first line
of therapy for recurrent AF...
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