Dialogues in Cardiovascular Medicine - Vol 9 . No. 4 . 2004






Randomized trial of an education and support intervention to prevent readmission of patients with heart failure
H. M. Krumholz, J. Amatruda, G. L. Smith, J. A. Mattera, S. A. Roumanis, M. J. Radford, P. Crombie, V. Vaccarino

One of the less frequently addressed issues in the management of heart failure is the high readmission rate to hospital after an initial inpatient episode...



Long-term trends in the incidence of and survival with heart failure
D. Levy, S. Kenchaiah, M. G. Larson, E. J. Benjamin, M. J. Kupka, K. K. Ho, J. M. Murabito, R. S. Vasan

Over recent decades, there have been significant advances in the treatment of hypertension, historically the leading cause of heart failure...



Differential gene expression and genomic patient stratification following left ventricular assist device support
B. C. Blaxall, B. M. Tschannen-Moran, C. A. Milano, W. J. Koch

Donor organs required for heart transplantation are in limited supply and for many patients the wait for transplant surgery proves too long, with fatal deterioration before organ availability...



Clinical assessment identifies hemodynamic profiles that predict outcomes in patients admitted with heart failure
A. Nohria, S. W. Tsang, J. C. Fang, E. F. Lewis, J. A. Jarcho, G. H. Mudge, L. W. Stevenson

Despite the introduction of many new therapies for the treatment of chronic heart failure, morbidity and mortality remain high...



Effect of enalapril on 12-year survival and life expectancy in patients with left ventricular systolic dysfunction: a follow-up study
P. Jong, S. Yusuf, M. F. Rousseau, S. A. Ahn, S. I. Bangdiwala

This paper describes the long-term outcomes of patients recruited into the Studies Of Left Ventricular Dysfunction (SOLVD)...



Targeted anticytokine therapy in patients with chronic heart failure: results of the Randomized Etanercept Worldwide Evaluation (RENEWAL)
D. L. Mann, J. J. McMurray, M. Packer, K. Swedberg, J. S. Borer, W. S. Colucci, J. Dijan, H. Drexler, A. Feldman, L. Kober, et al

Observation of elevated levels of tumor necrosis factor (TNF) in heart failure led to investigations into its possible role in the pathophysiology of the condition...



CRegenerative capacity of the myocardium: implications for treatment of heart failure
R. von Harsdorf, P. A. Poole-Wilson, R. Dietz

This review article describes in some depth novel approaches to the management of heart failure and discusses the rationale for, as well as the limitations of, each treatment...



Do we understand who benefits from resynchronisation therapy?
O. A. Breithardt, P. Claus, G. R. Sutherland

Cardiac resynchronization therapy (CRT) is now an accepted tool in the treatment of severe left ventricular dysfunction...



Hypertrophic cardiomyopathy
P. Elliott, W. J. McKenna

Hypertrophic cardiomyopathy (HCM) was first described in 1869...



A meta-analysis of the effects of treatment on left ventricular mass in essential hypertension
A. U. Klingbeil, M. Schneider, P. Martus, F. H. Messerli, R. E. Schmieder

As mentioned in the preceding summary, one of the major questions that has plagued physicians involved in the treatment of hypertension over the last 40 years, with the development of various classes of antihypertensive drug with different mechanisms of action, is whether any drug class is superior to any other in terms of preventing cardiovascular morbidity and mortality...






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