How important is it to assess and attempt
to
control cardiac fibrosis in hypertension? |
Fibrous tissue accumulation is
an integral feature of the adverse
structural remodeling of myocardial
tissue following a cardiac insult.
Given the importance of fibrous
tissue in leading to myocardial
dysfunction and failure, noninvasive
assessment of fibrosis could
prove a clinically useful tool, particularly
given the potential for
cardioprotective and cardioreparative
pharmacological strategies.
This approach represents an exciting
and innovative strategy, and
available data set the stage for
large-scale and long-term trials,
where this noninvasive assessment
of myocardial fibrosis in patients
with hypertensive heart disease
and other cardiac diseases could
prove useful...
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