The influence of dietary fats on serum lipid levels in man
E. H. Ahrens, J. Hirsch, W. Insull, T. T. Tsaltas, R. Bloomstrand, M. L. Peterson
One of the most striking aspects of this seminal
paper is the quality of the research presented,
and the profound questions that are
raised about the fundamental influence of
the quantity and quality of dietary fats upon
the serum lipid profile...
Prediction of serum cholesterol responses of man to changes
in fats in the diet
A. Keys, J. T. Anderson, F. Grande
This paper is remarkable for several reasons.
Firstly, it sets out to achieve what at first sight
appears to be a near-impossible task, that is,
to demonstrate a method for predicting serum
cholesterol changes from the dietary source...
Quantitative effects of dietary fat on serum cholesterol in man
D. M. Hegsted, R. B. McGandy, M. L. Myers, E. J. Stare
Both similarities and striking differences are to be
found between this paper and previous studies
seeking to discover a mathematical prediction
of the effect of dietary lipids upon serum cholesterol...
Serum cholesterol response to changes in the diet.
IV. Particular saturated fatty acids in the diet
A. Keys, J. T. Anderson, F. Grande
Amidst the abundance of regression analyses
and equation-solving that characterizes both
this paper and the previous one from this
group that is discussed in these summaries,
there does appear to be at least one clear
conclusion: dietary stearic acid does not have a serum
cholesterol–raising effect...
The Seven Countries Study: 2289 deaths in 15 years
A. Keys, A. Menotti, C. Aravanis, H. Blackburn, B. S. Djordjevic, R. Buzina, A. S. Dontas,
F. Fidanza, M. J. Karvonen, N. Kimura, et al
Epidemiological studies such as this rely on a long
duration of follow-up (in this case 15 years) to
obtain significant results, a period made all the
more poignant in this case by the fact that two
of the authors died before it reached publication...
Comparison of effects of dietary saturated, monounsaturated,
and polyunsaturated fatty acids on plasma lipids
and lipoproteins in man
F. H. Mattson, S. M. Grundy
This study was published at a time when questions
were being raised about the long-term
safety of polyunsaturated fats, and as a result
carbohydrates were being recommended as a
replacement for saturated fatty acids in the diet...
Comparison of monounsaturated fatty acids and carbohydrates
for lowering plasma cholesterol
S. M. Grundy
Unlike previous studies focusing upon the
comparison between polyunsaturated and
saturated fats, this is one of the first studies
to compare the impact upon plasma lipids
of diets rich in carbohydrate (consequently
low in fat) with those rich in monounsaturated fats...
Effect of dietary stearic acid on plasma cholesterol
and lipoprotein levels
A. Bonamone, S. M. Grundy
An important question regarding the relative
effects of different saturated fats upon the
serum lipid profile is addressed in this study:
do all saturated fats have a deleterious influence?)...
Effects of dietary trans fatty acids in high-density and low-density
lipoprotein cholesterol levels in healthy subjects
R. P. Mensik, M. B. Katan
Prior to the publication of this paper, there were
reports that drew conflicting conclusions about
the influences of dietary fatty acids upon serum
lipids...
Effects of a dietary portfolio of cholesterol-lowering foods vs
lovastatin on serum lipids and C-reactive protein
D. J. Jenkins, C. W. Kendall, A. Marchie, D. A. Faulkner, J. M. Wong, R. de Souza, A. Eman,
T. L. Parker, E. Vigden, K. G. Lapsley, et al
Jenkins et al investigate the intriguing hypothesis
that dietary modification may have comparable
benefits to a first generation statin (lovastatin)
in altering low-density lipoprotein (LDL) cholesterol,
high-density lipoprotein (HDL) cholesterol,
and C-reactive protein (CRP) levels...
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