Immunoglobulins and left ventricular structure and function
in pediatric HIV infection
S. E. Lipshultz, E. J. Orav, S. P. Sanders SP, S. D. Colan
Progressive left ventricular (LV) dilation and inadequate
left ventricular hypertrophy place human
immunodeficiency (HIV)-infected children at increased
risk for congestive heart failure (CHF)
or cardiac death...
Cardiac dysfunction and mortality in HIV-infected children:
the prospective P2C2 HIV Multicenter study
S. E. Lipshultz, K. A. Easley, E. J. Orav, S. Kaplan, T. J. Starc, J. T. Bricker, W. W. Lai,
D. S. Moodie, G. Sopko, S. D. Colan
Abnormalities of left ventricular structure and
function are common in human immunodeficiency
virus (HIV)-infected children and are
often persistent and progressive. The clinical
importance of these echocardiographic abnormalities
in HIV-infected children was unclear before this
study was performed...
Heart muscle disease related to HIV infection:
prognostic implications
P. F. Currie, A. J. Jacob, A. R. Foreman, R. A. Elton, R. P. Brettle, N. A. Boon
By the early 1990s, there had been a few studies
published in the medical literature relating human
immunodeficiency virus (HIV) infection to
its associated cardiac comorbidities (pericardial
effusions, arrhythmias, malignancy, endocarditis,
and cardiomyopathy)...
Diagnosis, prediction, and natural course of HIV-1 proteaseinhibitor–
associated lipodystrophy, hyperlipidaemia,
and diabetes mellitus: a cohort study
A. Carr, K. Samaras, A. Thorisdottir, G. R. Kaufmann, D. J. Chisho, D. A. Cooper
The use of protease inhibitors (PI) as a component
of the human immunodeficiency virus (HIV)
treatment regimen in the late 1990s ushered
in improved outcomes, but it also brought
along derangements in the homeostasis of lipid
and glucose metabolism...
Cardiovascular status of infants and children of women infected
by HIV-1 (P2C2 HIV): a cohort study
S. E. Lipshultz, K. A. Easley, E. J. Orav, S. Kaplan, T. J. Starc, J. T. Bricker, W. W. Lai,
D. S. Moodie, G. Sopko, M. D. Shluchter; Pediatric Pulmonary and Cardiovascular Complications
of Vertically Transmitted HIV Infection (P2C2 HIV) Study Group
Issues concerned with vertical transmission of human
immunodeficiency virus (HIV) had focused
mainly on prevention of perinatal infection, but the
work of the Pediatric Pulmonary and Cardiovascular
Complications of Vertically Transmitted HIV Infection
(P2C2 HIV) Study Group shifted the focus to a systematic
investigation of this vulnerable population...
Mild dilated cardiomyopathy and increased left ventricular mass
predict mortality: the prospective P2C2 HIV multicenter study
S. D. Fisher, K. A. Easley, E. J. Orav, S. D. Colan, S. Kaplan, T. J. Starc; J. T. Bricker, W. W. Lai,
D. S. Moodie, G. Sopko, S. E. Lipshultz; Pediatric Pulmonary and Cardiovascular Complications
of Vertically Transmitted HIV Infection (P2C2 HIV) Study Group
The P2C2 HIV (Pediatric Pulmonary and Cardiovascular
Complications of Vertically Transmitted
Human Immunodeficiency Virus Infection
(P2C2 HIV) Study Group had published many
findings on the plight of children born to HIVinfected
mothers...
Cardiovascular and cerebrovascular events in patients treated
for immunodeficiency virus infection
S. A. Bozette, C. F. Ake, H. K. Tam, S. W. Chang, T. A. Louis
Previous studies had reported a host of metabolic
abnormalities associated with human immunodeficiency
virus (HIV) infection and treatment,
which included altered regulation of glucose,
insulin, cholesterol and triglycerides, are very
common...
Cardiovascular risk and body-fat abnormalities
in HIV-infected adults
S. Grinspoon, A. Carr
Grinspoon and Carr provide a masterful review
of the current findings in the metabolic derangements
in HIV-infected adults as they
pertain to lipodystrophy and cardiovascular
disease. Beyond the summarization of information
known to date, they provide a clear and concise
set of figures, tables, as well as synthesized recommendations
for screening and intervention...
Impact of HIV and highly active antiretroviral therapy
on leukocyte adhesion molecules, arterial inflammation,
dyslipidemia, and atherosclerosis
S. D. Fisher, T. L. Miller, S. E. Lipshultz
Highlighting the role that highly active antiretroviral
therapy (HAART) has played in
both extending the lives of human immunodeficiency
virus (HIV)-infected adults as
well as reducing the risk of early death from
opportunistic infections, the authors of this review tackle
the issue of cardiovascular comorbidity...
Class of antiviral drugs and the risk of myocardial infarction
N. Friis-Moller, P. Reiss, C. A. Sabin, R. Weber, A. Monforte, W. El-Sadr, R. Thiebaut,
S. De Wit, O. Kirk, E. Fontas, et al; DAD Study Group
Previous findings from the DAD (Data Collection
on Adverse Events of Anti-HIV [human immunodeficiency
virus] Drugs) Study Group had shown
an increased risk of myocardial infarction associated
with duration of antiretroviral therapy
(ART). In this study, the authors investigated the risk of
myocardial infarction with specific ART drug class...
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